Abstract
Various scaffold fabrication methods have been explored to enhance the cell interaction effects and mechanical properties of scaffolds in bone regeneration. Rapid prototyping (RP) for tissue engineering is a useful technology that may provide a potential scaffolding structure to regenerate, restore, and repair a damaged bone tissue or organ, that is, RP is a promising tissue engineering technique through a 3D scaffold fabrication by using a computer-aided design/computer-aided manufacturing system. In this study, 3D β-tricalcium phosphate (β-TCP) scaffolds were fabricated by a novel direct-write assembly method. The mechanical property of β-TCP scaffolds was analyzed by stress-strain curves by using a compression testing machine. Furthermore, an in vitro CCK-8 assay of osteosarcoma MG-63 cells showed the significant cell attachment and proliferation in the β-TCP scaffold.
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