Abstract

In this paper, we present an efficient and simple approach to fabricate a novel microscaffold with high pattern fidelity and an open porous structure for modular tissue engineering. We characterized the microstructure, explored the formation mechanism, and evaluated the growth of cells in the microscaffold. Moreover, microscaffold blocks were assembled by surface tension-driven assembly to construct engineered tissue with controlled cell distribution and cell interactions. This microscaffold could be potentially applied as a building block to create 3D biomimetic engineered tissue.

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