Abstract
Obsessive-Compulsive Disorder (OCD) is characterized by the presence of obsessions (i.e. intrusive thoughts/images/impulses) and compulsions (i.e. repetitive actions to prevent/mitigate distress). Cognitive Behavioral Therapy (CBT) with exposure and ritual prevention is a first-line treatment for pediatric OCD, yet personalized medicine could improvement response rates. Herein, we identify brain structural markers of CBT response in pediatric OCD, representing stable and easily-measured metrics to help precision medicine efforts in youth.
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