Abstract

Research reveals distinct psychiatric profiles and substance-specific manifestations of impulsivity among opiate and stimulant dependent individuals. However, findings have been inconclusive, due in part to the high rates of polysubstance dependence, which limit investigations of the common vs. specific effects of different drug classes. The aim of the present study is to examine sibling correlations on psychiatric symptoms and dimensions of impulsivity among individuals with ‘pure’ heroin and amphetamine dependence in Bulgaria, in order to explore their utility as common vs. specific endophenotypes for opiate and stimulant dependence.

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