Abstract
Evidence suggests early sensory processing is impaired in first episode psychosis (FEP) patients, measured in sensory gating (P50) and mismatch negativity (MMN) event-related potentials (ERPs). However, studies of the longitudinal course of these deficits are rare, so much less is known about the changes over time across the early course of the disease. This study aims to 1) examine P50 and MMN changes between baseline, 12-month, and 24-month follow-ups in FEP patients, and 2) investigate the association of ERPs with functional and clinical measures.
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