Abstract

Neurolymphomatosis (NL) is an uncommon infiltration of peripheral and/or cranial nerve roots from mostly B-cell non-Hodgkin's lymphoma and is extremely rare (1.9%). Clinical diagnosis is difficult as its symptoms are similar to viral, inflammatory, and demyelinating pathologies. We present a 58-year-old female patient who had been diagnosed with lymphoma and presented with progressive weakness in the lower extremity and facial paresthesia. After the preliminary diagnosis of Guillain-Barre Syndrome, the patient did not respond to intravenous immunoglobulin (IVIg) treatment. F18-FDG PET/CT images showed extensive spinal nerve roots, cranial nerves, and solid organ involvement, and she was diagnosed with NL.

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