Abstract
AKR X DBA/2 (AKD2F1) mice resist growth of injected spontaneous AKR lymphoma cells. In vitro, normal F1 responder cells generate Thy-1 positive effector cells specifically cytotoxic for the sensitizing antigens of parental AKR normal or lymphoma cells. The possibility is considered that the homozygous normal and neoplastic AKR cells express antigenic determinants, analogous to hemopoietic histocompatibility (Hh) antigens, which are recognized by the F1 hybrid, resulting in in vivo tumor resistance and in vitro cell-mediated cytotoxicity.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
