Abstract
Gastrointestinal stromal tumor (GIST) is a rare group of stromal or connective tissue tumors that arises from mesenchymal cells of the gastrointestinal tract characterized by positive expression of c-Kit. Accurate assessment of GIST tumor spread by anatomic imaging techniques can be difficult in poorly defined tumor lesions such as bowel, peritoneal, or bone metastases. Therefore, an underestimation of tumor burden may result. In addition, such techniques cannot discriminate early tumor response to therapy. In this rare case, baseline F-18 FDG PET imaging proved to be more efficient than CT in delineating the true metastatic tumor burden and the early-on excellent response to medication targeting cellular tyrosine kinase.
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