Abstract

Abstract: Aggressive natural killer (NK) cell leukemia is a rare hematologic malignancy characterized by diffuse infiltration of bone marrow and leukemic involvement of organs. Detection of organ involvement is challenging using morphologic imaging procedures. We report a case of aggressive NK-cell leukemia detected by F-18 fluorodeoxyglucose positron emission tomography/computed tomography. Positron emission tomography/computed tomography might be a valuable tool enabling diagnosis and comprehensive staging of NK cell leukemia.

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