Abstract

v LIST OF FIGURES viii LIST OF TABLES ix CHAPTER 1: INTRODUCTION 1 A) Clinical challenge: Cocaine Dependence B) Neural circuitry of cocaine addiction C) Attentional bias and relapse in substance dependence D) Attentional bias: Current measures and limitations E) Eye movements: Saccades F) Circuitry of saccadic eye-movements G) Clinical utility of saccadic eye-movements H) Neuroanatomical overlap between saccadic function & cocaine impairment I) Hypotheses and specific aims CHAPTER 2: ANTI-SACCADE ERROR RATES AS PREDICTORS OF RELAPSE IN COCAINE-DEPENDENT SUBJECTS 30

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