Abstract
INTRODUCTION: Scleritis is often the first clinical manifestation of a systemic disease. Identifying the underlying disease is critical for proper treatment and prognosis. Approximately 43% of scleritis cases are idiopathic, 48% are related to skeletal and connective tissue diseases and 7% are infection related. Malignancy is rarely associated with scleritis. Two previous reports of malignancy (direct scleral involvement with choroidal melanoma and metastatic adenocarcinoma of unknown origin) were associated with an initial presentation of scleritis.
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