Eyelid Tumors: Clinical Data from an Eye Center in Ankara, Turkey

Fatih Cakir Gundogan,Umit Yolcu,Fahri Sahin,Salih Uzun,Mustafa Ozturk,Abdullah Ilhan,Omer Faruk Sahin,Ahmet Tas,Uzeyir Erdem,Hakan Cermik,Salih Altun,Sukru Ozaydin

doi:10.7314/apjcp.2015.16.10.4265

Abstract

The aim of the study was to explore the distribution of eyelid tumors in Ankara, the capital city of Turkey, from a histopathological point of view. Medical records of 1,502 patients who had eyelid surgery because of tumoral lesions were retrospectively reviewed after obtaining institutional review board approval. A total of 1,541 lesions with histopathologic diagnosis were included. Inflammatory tumoral lesions were excluded. The lesions were categorized into three groups according to the origin: epidermal, adnexal tumors and 'others', including melanocytic, neural and vascular lesions. Of the total of 1,541, 908 lesions were epidermal in origin. Only 22 (1.5%) were malignant, and 6.0% was premalignant lesions such as actinic keratosis and Bowen's disease. Twenty-one of 22 malignant lesions were basal cell carcinoma. There was only one patient with squamous cell carcinoma and no sebaceous cell carcinoma. Among the benign tumors (92.5%), squamous papilloma was the most frequent (21.8% of all lesions). The other frequent lesions were nevus (17.6%), seborrheic keratosis (17.3%), hydrocystomas (10.6%), xanthelasma (7.6%) and epidermal cysts (7.2%). The results of this study are in accordance with published literature. The absence of sebaceous cell carcinomas needs to be stressed.

Highlights

The aim of the study was to explore the distribution of eyelid tumors in Ankara, the capital city of Turkey, from a histopathological point of view
This study aimed to explore the distribution of eyelid tumors as diagnosed by histopathologic specimens in Sincan region of Ankara, the capital city of Turkey
Five patients with basal cell carcinoma, two patients with xanthelasma, 4 patients with chalazion were misdiagnosed as squamous papilloma

Summary

Introduction

The aim of the study was to explore the distribution of eyelid tumors in Ankara, the capital city of Turkey, from a histopathological point of view. Some malignant tumors may mimic benign neoplastic and, inflammatory conditions and cause late diagnosis. A wide variety of benign and malignant tumors can originate because of the existence of many different tissue types in the eyelids (Deprez and Uffer, 2009). Different cell types of epidermis, Meibomian, Zeis, Moll, Wolfring and Krause glands, eyelash follicles may all cause eyelid tumors. Some studies emphasized the importance of sun exposure in the emergence and the use of glasses in the prevention of cancers including the eye and eyelids.(Bhurgri et al, 2003; Turgay et al, 2005; Gajda and Kaminska-Winciorek, 2014) many types of eyelid tumors may be diagnosed from a clinical point of view, some should be diagnosed with pathological specimens. A small number of large studies exist exploring the frequency of eyelid lesions from different sites of the world (Abdi et al, 1996; Ni, 1996; Xu et al, 2008)

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