Abstract

The effect of comorbid ADHD on oculomotor abnormalities in boys with Tourette syndrome (TS) was determined using three saccade tasks to examine the planning and execution of eye movements in a study at the Kennedy Krieger Institute and Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD.

Highlights

  • The effect of comorbid ADHD on oculomotor abnormalities in boys with Tourette syndrome (TS) was determined using three saccade tasks to examine the planning and execution of eye movements in a study at the Kennedy Krieger Institute and Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD

  • Latency of prosaccades was prolonged in both patient groups (TS-only and TS+ADHD) compared to controls, which indicates that TS is associated with delay in initiation of oculomotor responses

  • Response inhibition errors on aritisaccade tasks and memory-guided saccade task were increased in boys with TS+ADHD compared to the TS-only group, suggesting that comorbid ADHD is associated with deficits in response inhibition and excessive variability in motor response to a visual stimulus

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Summary

Introduction

EYE MOVEMENTS IN TOURETTE SYNDROME & COMORBID ADHD The effect of comorbid ADHD on oculomotor abnormalities in boys with Tourette syndrome (TS) was determined using three saccade tasks to examine the planning and execution of eye movements in a study at the Kennedy Krieger Institute and Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD. Subjects in 3 groups, ages ranging from 7.8-14.6 years (means 1011 yrs) included 14 with TS-only, 11 with TS+ADHD, and 10 controls.

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