Abstract
Studies involving the quantitation of eye irritation produced by experimental exposure of humans to synthetic atmospheres are discussed. The principal methods used are panel measurements of intensity, threshold, or response delay. Advantages and difficulties of each method are reviewed, as well as characteristics of the data generated and appropriate means of manipulating the data. Evidence regarding the possible chemical identity of irritants in photochemical smog is discussed, leading to the conclusion that not all observed eye irritation is accounted for by additive effect of formaldehyde, acrolein, and peroxyacyl nitrates. Implications of the findings for air pollution control policies are considered. As one of the undesirable manifestations of photochemical smog, eye irritation has been the subject of a number of studies in recent years. This article reviews several of these studies with particular reference to those aspects relevant to air pollution research and air pollution control policy.
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