Extremely rare synovial chondrosarcoma arising from the elbow joint: case report and review of the literature

Abstract

Primary synovial chondromatosis is benign disease of the mucosal membrane in the joint. This disease often affects the knee joint but rarely the elbow joint. 14 Mueller T. Barthel T. Cramer A. Werner A. Gohlke F. Primary synovial chondromatosis of the elbow. J Shoulder Elbow Surg. 2000; 9: 319-322 Abstract Full Text Full Text PDF PubMed Scopus (29) Google Scholar Chondrosarcoma, however, is a common malignant bone tumor that usually arises from cartilaginous tissue but which can also arise de novo in extraskeletal tissues. Synovial chondrosarcoma arising from chondromatosis is one of the rarest types of chondrosarcoma. 2 Bertoni F. Unni K.K. Beabout J.W. Sim F.H. Chondrosarcomas of the synovium. Cancer. 1991; 67: 155-162 Crossref PubMed Scopus (145) Google Scholar To our knowledge, only 31 patients with a malignant transformation of synovial chondromatosis have been reported (Table I). 1 Anract P. Katabi M. Forest M. Benoit J. Witvoët J. Tomeno B. Synovial chondromatosis and chondrosarcoma. A study of the relationship between these two diseases. Rev Chir Orthop Reparatrice Appar Mot. 1996; 82: 216-224 PubMed Google Scholar , 2 Bertoni F. Unni K.K. Beabout J.W. Sim F.H. Chondrosarcomas of the synovium. Cancer. 1991; 67: 155-162 Crossref PubMed Scopus (145) Google Scholar , 3 Blokx W. Rasing L. Veth R. Pruszczynski M. Late malignant transformation of biopsy proven benign synovial chondromatosis: an unexpected pitfall. Histopathology. 2000; 36: 564-572 Crossref PubMed Scopus (25) Google Scholar , 4 Davis R. Hamilton A. Biggard J. Primary synovial chondromatosis: a clinicopathologic review and assessment of malignant potential. Hum Pathol. 1998; 29: 683-688 Abstract Full Text PDF PubMed Scopus (187) Google Scholar , 5 Dunn E. McGavran M. Nelson P. Greer R. Synovial chondrosarcoma: report of a case. J Bone Joint Surg Am. 1974; 56: 811-813 PubMed Google Scholar , 6 Hallam P. Ashwood N. Cobb J. Fazal A. Heatley W. Malignant transformation in synovial chondromatosis of the knee. Knee. 2001; 8: 239-242 Abstract Full Text Full Text PDF PubMed Scopus (38) Google Scholar , 7 Hamilton A. Davis R. Hayes D. Mollan R. Chondrosarcoma developing in synovial chondromatosis: a case report. J Bone Joint Surg Br. 1987; 69: 137-140 PubMed Google Scholar , 8 Hamilton A. Davis R.I. Nixon J.R. Synovial chondrosarcoma complicating synovial chondromatosis. Report of a case and review of the literature. J Bone Joint Surg Am. 1987; 69: 1084-1088 PubMed Google Scholar , 9 Hermann G. Klein M. Fikry I. Kenan S. Synovial chondrosarcoma arising in synovial chondromatosis of the right hip. Skeletal Radiol. 1997; 26: 366-369 Crossref PubMed Scopus (50) Google Scholar , 10 Kenan S. Fikry I. Klein M. Lewis M. Case report 817. Skeletal Radiol. 1993; 22: 623-626 Crossref PubMed Scopus (64) Google Scholar , 12 King J. Harlan S. Fechner R. Vanderpool D. Synovial chondrosarcoma of the knee joint. J Bone Joint Surg Am. 1967; 49: 1389-1396 PubMed Google Scholar , 15 Perry B. McQueen D. Lin J. Synovial chondromatosis with malignant degeneration to chondrosarcoma: report of a case. J Bone Joint Surg Am. 1988; 70: 1259-1261 PubMed Google Scholar , 16 Sah A. Geller D. Mankin H. Rosenberg A.E. Delaney T.F. Wright C.D. et al. Malignant transformation of synovial chondromatosis of the shoulder to chondrosarcoma. J Bone Joint Surg Am. 2007; 89: 1321-1328https://doi.org/10.1016/j.ejrad.2009.05.029 Abstract Full Text Full Text PDF PubMed Google Scholar , 17 Taconis W.K. van der Heul R.O. Taminiau A.M. Synovial chondrosarcoma: report of a case and review of the literature. Skeletal Radiol. 1997; 26: 682-685 Crossref PubMed Scopus (43) Google Scholar , 19 Wuisman P.I. Noorda R.J. Jutte P.C. Chondrosarcoma secondary to synovial chondromatosis. Report of two cases and a review of the literature. Arch Orthop Trauma Surg. 1997; 116: 307-311 Crossref PubMed Scopus (42) Google Scholar , 20 Zamora E.E. Mansor A. Vanel D. Errani C. Mercuri M. Picci P. et al. Synovial chondrosarcoma: report of two cases and literature review. Eur J Radiol. 2009; 72: 38-43https://doi.org/10.1016/j.ejrad.2009.05.029 Abstract Full Text Full Text PDF PubMed Scopus (17) Google Scholar AWD, alive with disease; CS, chondrosarcoma; DOD, dead of disease; ND, not documented; NED, no evidence of disease.