Extremely bulky triarylphosphines incorporating 2,6-diisopropylphenyl substituents; consideration of steric shielding and steric pressure

Abstract

The geometry of 15 triarylphosphines which differ in the nature of the substituents at the 2 and 6 positions of one or more phenyl rings are compared. The sum of angles around phosphorus, ∑{∠CPC}, is used as the primary measure of steric bulk. The roles of substituents, which act as steric shields surrounding the phosphine lone pair and of those which generate steric pressure and cause flattening of the C 3P pyramid are identified. Both crystallographic and computational (HF 6-31G(d)) structures are used to assess ∑{∠CPC}, the pyramidalization angle α, the average C–P distance, and the helical twist angle of the aryl rings β. All of these parameters confirm that ortho-2,6-diisopropyl substituted aryl groups generate the most sterically congested triarylphosphines. Comparison to Tolman cone angles are made where these are available.