Abstract

Paper is devoted to answer the question: “How large is the largest red blood cell in a blood sample?” The red cell diameter was measured by photographing the cell in an interferometric microscope and processing the hologram by a numerical procedure of superresolution, which yields an improved resolution of 0.02 μm. Data on the largest cells in samples of specific size were collected and analyzed according to the theory of extreme-value statistics. It was found that the statistical distribution of the largest cells follows the asymptote derived for initial distribution of the exponential type. When the parameters of the asymptotic extreme distribution are determined from the observed data, the expected largest red cell in a sample of arbitrary size n can be easily determined as a function of n. For example, for the group of young adult male students examined the predicted largest diameter in a population of 10 8 red blood cells lies between 15.66 and 17.06 μm.

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