Abstract

Extreme Drug Resistance in<i>Acinetobacter baumannii</i>Infections in Intensive Care Units, South Korea

Highlights

  • Difference in adaptability responses to stress has been observed amongst bird species, strains, and individuals

  • Corticosterone levels Animals treated with 1-24 adrenocorticotropic hormone (ACTH) showed higher plasma corticosterone levels (p < 0.0001) compared to nontreated ones

  • A single transcript was found to be up-regulated in both experiments, with the group with a higher response to treatment showed a higher expression for that transcript compared to the control group (Experiment 1) or to the lower response to 1-24 ACTH injection (Experiment 2)

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Summary

Introduction

Difference in adaptability responses to stress has been observed amongst bird species, strains, and individuals. Components of the HPA axis, one of the internal systems involved in homeostasis re-establishment following stress, could play a role in this variability of responses. Several systems, mainly the hypothalamic-pituitary-adrenal (HPA) axis, the autonomic nervous system (ANS) [2,3], and the immune system [4] are called into action to re-establish homeostastis. This is done by setting up a cascade of regulatory mechanisms [5,6], resulting in a mobilization of energy and a shift in metabolism with detrimental effects on growth performance and efficiency of feed utilization. The response of adrenal glands to ACTH seems to be variable in numerous species, including rat [27], pig [11,1316] and quail [10,17] and difference in adrenal responsiveness may play a role in the variability of the response to stress.

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