Extrapyramidal manifestations accompanying treatment with neuroleptics

Abstract

The manifestations of neuroleptic syndrome depending on the duration of treatment with neuroleptics as well as the combinations of various extrapyramidal disorders are studied in 50 women aged 28 to 69 with the diagnosis schizophrenia. Parkinsonism manifestations are observed in 32 patients, various symptoms of late dyskinesia are observed in 30 women. Such motor disorders as lingua-bucco-mental dyskinesias, motor anxiety syndrome, dystonia in hands, tongue tremor, blepharospasm, usual manipulations are often revealed. There were extrapyramidal disorders in more than 60% of the patients. Late dyskinesia and parkinsonism syndrome depend on the treatment duration, and their combination is not typical.