Extrapulmonary inflammatory myofibroblastic tumor: Comparation of CT and MRI findings and pathology

Abstract

Objective To explore diagnostic value of CT and MRI inflammatory myofibroblastic tumor (IMT) and to compare with pathology. Methods CT and MRI findings of 8 patients with IMT confirmed by operation and pathology were retrospectively analyzed, and compared with pathology. The pathological basis of the CT, MRI expression was explored. Results Among the 8 cases, 7 cases received CT examination (of which 1 cases also underwent MRI examination), 1 received MRI examination. The main CT signs of IMT showed as follows: 2 cases were relatively homogeneous in density, the other 5 cases were nonhomogeneous density, including of 3 cases with obvious uneven enhancement. Neighboring bone were destructed in 3 cases. On MR imaging: 1 case showed even enhancement, another showed around the high aparent heterogeneous enhancement. Fibroblast proliferation, interstitial collagen, capillary hyperplasia and mucus degeneration and large amounts of inflammatory cell infiltration could be seen pathologically. Conclusions CT and MRI findings of extrapulmonary IMT are well corresponded with pathology. CT and MRI examinations can help to make the diagnosis and differential diagnosis. It is very useful for mapping the extension of IMT, relationship with adjacent organs, choosing the perfect treatment ways and preoperative diagnosis. Key words: Fibroma; Tomography, X-ray computed; Magnetic resonance imaging; Pathology