Abstract
Rosai Dorfman disease (RDD) also referred to as sinus histiocytosis with massive lymphadenopathy is a rare non-neoplastic lymphoproliferative disease with unknown etiology and pathogenesis first described by Rosai and Dorfman in 1969. It is characterized by histiocytic proliferation of lymphatic sinuses, which primarily involves the lymph nodes, but has an extranodal tendency. Frequently encountered extranodal sites in the head-and-neck region is paranasal sinuses and nasal cavity, orbit, parotid gland, and middle ear. We present a case of RDD occurring in the nasal cavity of a 28-year-old female from Nigeria. RDD should be considered a differential diagnosis in any patient with benign sinonasal mass especially arising from the nasal septum with massive cervical lymphadenopathy.
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