Abstract
Lymphoma is classified into Hodgkin's lymphoma (HL) or non-HL (NHL). NHL is more commonly found in the head-and-neck region. Majority of the extra-nodal location for NHL is the Waldeyer's ring. These NHLs are rarely found in the sinonasal tract. The clinical presentations of the extra-nodal sinonasal NHL are usually nonspecific. Computed tomography scan of the head-and-neck region usually reveals the extent of the neoplasm. However, the confirmatory diagnosis is done by the tissue biopsy and study of the immunohistochemistry. The treatment modality is controversial in regards to the best therapeutic option. Chemotherapy or concomitant chemoradiation is an important treatment option. Surgery has a limited role for the treatment of the sinonasal NHL. The increasing prevalence and the significant morbidity of the sinonasal NHL are often critical to do early diagnosis and treatment. Early diagnosis along with continuous monitoring and close follow-up are recommended for the early diagnosis and effective treatment. Clinicians should have knowledge regarding the clinical presentations of the extranodal NHL. Correct and timely diagnosis is helpful for effective treatment of the sinonasal NHL. The aim of this review article is to discuss about the etiopathology, clinical presentations, investigations, and current treatment of the sinonasal NHL.
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