Extramedullary Plasmacytoma of Nasal Cavity: A Case Report

Abstract

Plasmacytoma is a rare anomaly and discrete solitary mass of neoplastic monoclonal plasma cells. It was first described by Schridde in 1905. Extramedullary plasmacytoma (EMP) mostly occurs during the fifth and seventh decades of life and is rarely diagnosed in younger patients. A common clinical symptom includes epistaxis, rhinorrhea, a sore throat, dysphonia and hemoptysis and is usually managed by surgery with or without radiotherapy. Plasmacytoma is a malignant disease that present either in bone marrow (medullary plasmacytoma), within the bone (solitary plasmacytoma of bone), or outside of bone, as the EMP. EMP accounts for 3% of all plasma cell tumors and approximately 90% of EMP affect the head and neck region commonly affecting the nasal cavity, paranasal sinuses, tonsillar fossa and oral cavity.