Abstract
Extramedullary plasmacytoma (EMP) is defined as neoplastic proliferation of plasma cells in the soft tissue. It represents approximately 3% of all plasma cell neoplasms. EMP of the head and neck are very uncommon tumors, representing approximately 0.4% of all head and neck malignancies; amongst them, plasmacytoma of the maxilla is extremely rare. We present a rare case of EMP which had metastasized to multiple cervical lymph nodes and was associated with aspergillosis. The possibility of extramedullary plasmacytoma should be considered when an elderly patient presents with symptoms of recurrent rhinosinusitis not responding to conservative management and imaging shows a destructive soft tissue mass.
Highlights
Plasma cell neoplasms are a group of clinical disorders characterized by an uncontrolled monoclonal proliferation of plasma cells
extramedullary plasmacytoma (EMP) is defined as neoplastic proliferation of plasma cells in the soft tissue
Our case of EMP is extremely rare in the sense that it had metastasized to multiple cervical lymph nodes and was associated with aspergillosis
Summary
Plasma cell neoplasms are a group of clinical disorders characterized by an uncontrolled monoclonal proliferation of plasma cells. Localized forms of plasma cells neoplasms are solitary bone plasmacytoma (SBP) and extramedullary plasmacytoma (EMP); multiple myeloma (MM) is the disseminated type of this disorder.[1] EMP is defined as neoplastic proliferation of plasma cells in the soft tissue. Regional lymph nodes are invaded in less than 10% of EMP and 16% of patients progress to multiple myeloma.[1,3,4]
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