Extramammary Paget’s Disease of the Floor of Mouth Associated With Minor Salivary Gland Carcinoma and Concurrent Invasive Squamous Cell Carcinoma

Abstract

fibrillary acidic protein, vimentin, epithelial membrane antigen, actin, and desmin, supporting myoepithelial differentiation. Subsequently, a wide local excision was performed, and the defect was reconstructed with a bone graft and a fixed dental prosthesis. The tumor recurred after 10 years, presenting as a 1-cm mass expanding into the maxillary labial vestibule, beneath the nasal ala. A second wide local resection was performed, and the defect was reconstructed with an obturator. Eleven years after the initial presentation of the tumor, the patient is alive without evidence of disease. This tumor represents the unusual occurrence of an intraosseous salivary gland neoplasm, apparently arising from salivary tissue within the incisive canal.