Extraintestinal manifestations of inflammatory bowel diseases: arthropathy and arthritis

Abstract

Aim of review. To present major extraintestinal manifestations of inflammatory bowel diseases (IBD) and basic approaches to management of patients with ulcerative colitis and Crohn's disease having arthropathies and arthrites as extraintestinal manifestations. Summary. Ulcerative colitis and Crohn's disease represent the group of the diseases with unknown etiology encompassed by the term «inflammatory bowel diseases». IBDs are diseases with high social impact due to predominance of young patients of working-age and tendency to chronization of pathological process that leads to deterioration of life of patients and high demand in hospital stay. Ulcerative colitis and Crohn's disease have diverse clinical presentation with various intestinal complications and extraintestinal manifestations. The results of original studies corresponding to world literary data and data of the First European evidencebased consensus on extra-intestinal manifestations in inflammatory bowel disease are presented in this article. Presented data indicates severity and aggressive course of the IBD-associated arthropathies, their contribution to quality of life deterioration and risk of disability that requires diagnostics, timely and adequate pharmacological treatment with multidisciplinary approach. Resolution of this issue is not only an actual trend, but a demand of worldwide medical community for treatment and rehabilitation IBD patients as well. Conclusion. Meditate analysis of extraintestinal IBD manifestations, in particular IBD-associated arthropathy and arthritis, expands potential of time the diagnosis and adequate drug treatment to decrease disability risk and to improve quality of life of IBD patients.