Extragonadal teratoma in Zaria, Nigeria

Abstract

Background: Teratomas generally arise in the gonads, although several cases are reported in the extra gonadal sites. This study described the histopathological features of cases seen in a tertiary institution in Nigeria. Materials and Methods : This is a retrospective study of surgical biopsy specimens seen over 10-year period; data were analyzed with respect to age, sex, site, and histopathological characteristics and grading. The H and E, stained slides were retrieved in each case and reviewed microscopically by the authors. Results : Teratomas were observed in two adult and 37 infants and children. The age range was 5 days-38 years. Site of origin was Sacrococcygeal in 43.6%, retroperitoneal in10.3%, cervical in 12.8% and 20.5% in others. Mature teratomas account for 82.0% while 18.0% were immature teratoma. Three of the immature teratoma were grade III while the remaining four where grade II. There were more benign than malignant teratomas. Conclusion : Extragonadal teratomas are common in our environment with benign preponderance.