Abstract
Gastroesophageal reflux disease (GERD) is a common disease, affecting approx 40 million people in the United States alone. In fact, even this huge number is only an estimate, which is based on population surveys of the prevalence of frequent heartburn (the cardinal symptom of GERD) in the population. The GERD population would likely be even larger if the estimate encompassed individuals with extraesophageal manifestations of GERD, as well as heartburn sufferers. Extraesophageal manifestations of GERD, encompassing a spectrum of pulmonary and otolaryngologic disorders, may be the primary (or only) manifestation of GERD in some individuals. The implicated syndromes include posterior laryngitis, asthma, chronic cough, recurrent pneumonitis, chronic hoarseness, chest pain, pharyngitis, sinusitis, and dental disease.
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