Abstract
The aim of the present work was to test the hypothesis that the intact rat brain contains cells whose struc- tural organization and cytochemical properties make them similar to ependymocytes but which are locat- ed outside the ependymal layer. Experiments were performed on Wistar rats (n = 10). Ependymocytes were identified using immunocytochemical reactions for ezrin and vimentin and by light and confocal laser microscopy. The nervous system of the intact rat brain was found to contain, outside the ependymal layer, cells with structural and cytochemical similarity to typical ependymal cells. We suggest that extraependymal ependymocytes function as a reserve population of neural stem cells in the brain.
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