Abstract
THE bursa of Fabricius, a lymphoepithelial gland, was found by Glick et al. (1956) to be necessary in the production of antibodies to S. typhimurium. Since this original paper, Chang et al. (1957,1959) have confirmed and extended the role of the bursa in antibody production. In an initial trial, Glick (1958) reported higher antibody titers to sheepred-blood cells in bursectomized birds receiving a crude extract of bursa material than in the bursectomized controls. The object of this paper is to report additional results of injecting bursectomized birds with several fractions of bursa material.MATERIALS AND METHODSThe bursa was removed from 12-day-old New Hampshire chicks by making a lateral incision at the base of the tail just above the upper lip of the vent (Riddle and Tange, 1928; Glick, 1955; and Chang et al., 1957). The bursa was then grasped with curved forceps at its most anterior aspect and eased …
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