Extraction and recovery of chlorogenic acid from sunflower disks using a high‐efficiency system composed of deep eutectic solvents and macroporous resins

Abstract

Conventional methods to extract and recover chlorogenic acid (CGA) from plants exhibit plenty of flaws, like over-consumption of organic solvents, low extracting rate, and low enrichment efficiency. Herein, an ultrasound-assisted deep eutectic solvent extraction (UAE-DESs) was introduced to extract CGA from sunflower disks. And NKA-II macroporous resin was used as adsorbent to adsorb CGA from dilute DESs extracts. Then NKA-II was collected by filtration followed by desorption to obtain CGA separated from DESs. The extraction yield of CGA was 6.16 mg/g with liquid–solid ratio 31 ml/g, ultrasonic temperature 47°C, ultrasonic time 54 min, and deep eutectic solvent (DES) composed of choline chloride/1,4-butanediol (1/2, mol/mol) and water content 30% (w/w). After NKA-II enrichment, the recovery efficiency of CGA was 80.76% and the purity was 75.84%. Moreover, the recovered DESs could be reused during the extraction. The present research provided a time-saving, green, and sustainable method for extracting and recovering CGA from sunflower disks. Practical applications The research proposed a method for the extraction and recovery of CGA from sunflower disks by combining UAE-DESs and NKA-II macroporous resins. The combination of diluted DESs with macroporous resins can effectively overcome the disadvantages of DESs and provide an efficient method for the recovery of natural products. The CGA extracted can be applied in medicine, food, and other fields.