Abstract
Although misuse and abuse of Cannabis is well known, the health benefits have been proved by various biomedical studies. Tetrahydrocannabinol (THC) is the major active substance in leaves of Cannabis, which is the common target for drug testing. In field drug testing, oral fluid (OF) has its unique advantages over other specimens such as blood, urine, and hair. Thus the study of THC in OF is gaining popularity in Cannabis research. In this review, extraction methods are introduced in three categories, which are Liquid-Liquid Extraction (LLE), Solid Phase Extraction (SPE), and Supercritical Fluid Extraction (SFE). Examples of application with each method will be covered. Advantages and disadvantages of these methods will be compared. In addition, methods in analysis following extraction will be briefly discussed.
Highlights
Cannabis is referred to the leaves, stems, flowers and seeds from one type of hemp plants, Cannabis sativa (National Institute on Drug Abuse, 2016)
An increasing number of research had shown that Cannabis has plenty of health benefits for human, including treating glaucoma, controlling epileptic seizures and stopping cancer from spreading (NIHNational Eye institute, 2012; Pletcher, Vittinghoff, & Kalhan, 2012; Wallace et al, 2003)
Michigan State is in the process of seeking legalization of the recreational use of marijuana (Michigan State, 2008)
Summary
Cannabis is known as marijuana and by many other names. In history, it has been considered as a highly potential drug for recreational use, misuse and abuse. It has been considered as a highly potential drug for recreational use, misuse and abuse It is classified as Schedule I drug in the United States (United States Code 21 U.S.C §802(32)(A); United States Code 21 U.S.C. More than 20 states in USA have legalized medical marijuana, as well as the recreational use in Colorado, Alaska, Washington, Oregon and District of Columbia (National Conference of State Legislatures, 2016). We will summarize all the known methods in THC and THC-COOH extraction, as well as the related analytic techniques for them. In most of the studies, THC is the primary target analyte
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
