Abstract
The purpose of the present work is to investigate the feasibility and develop the methods for a clinical protocol of frameless extracranial stereotactic hypo-fractioned radiotherapy and radiosurgery, for the treatment of small secondary tumours. The main concept relies on the exploitation of opto-electronic technologies and multi-modal imaging to increase the target localization accuracy in treatment planning and dose delivery. Preliminary results show that the combined use of PET/CT imaging and opto-electronic respiratory gating is a promising technique for the reduction of localization uncertainties in extracranial stereotactic irradiation. The application of moderate deep inspiration breath-hold manoeuvres, guided by an opto-electronic localizer, can provide an effective improvement in localization accuracy.
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