Abstract
Introduction: The expression of genes that code for proteins involved in cellular calcium handling, such as sarco-endoplasmatic reticulum calcium ATPase (SERCA) and Na+-Ca2+ exchanger (NCX), as well as the expression of the brain natriuretic peptide (BNP) gene, is altered in a characteristic fashion in congestive heart failure. Several of the respective molecular pathways involve cytoplasmic calcium. Hypothesis: We hypothesized that contractile force and synthesis of these proteins depend on the extracellular calcium concentration in isometrically contracting human myocardium.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
