Extra-pleural Solitary Fibrous Tumour - A Rare Entity in the Oral Cavity Probably Induced by Childhood Radiotherapy

Abstract

Introduction: Solitary fibrous tumours (SFT) are rare, spindle cell neoplasms that are generally associated with serosal surfaces especially the pleura. Extra-pleural cases have been reported at sites including the abdomen, orbit, upper respiratory tract and oral cavity. SFTs are derived from mesenchymal cells and can develop following inflammation or injury to an area since spindle cells are a naturally occurring part of the body's response to insult. There is little evidence however to support SFTs arising post-radiotherapy. We present a case whereby we hypothesise that an oral SFT arose following childhood radiotherapy.