Extra luminal colonic gastrointestinal stromal tumor: a case report

Ibrahim Masoodi,Mushtaq Chalkoo,Arshad Rashid,Imtiyaz A Wani

doi:10.1186/1757-1626-2-7525

Abstract

IntroductionGastrointestinal stromal tumors are the commonest mesenchymal tumors of the gastrointestinal tract, the stomach and small intestine are the favored sites of occurrence. They rarely occur in the colon, rectum and esophagus. GIST is neoplasm of mesenchymal origin originating from precursors of the interstitial cells of cajal. The symptoms of gastrointestinal stromal tumor depend on the site and size of the tumor, and may include abdominal pain, gastrointestinal bleeding or signs of obstruction; small tumors may, however, be asymptomatic. Majority of the patients with gastrointestinal stromal tumor have bloody stools and abdominal pain as the commonest manifestation. We describe a young female with extra luminal colonic gastrointestinal stromal tumor presenting as mass abdomen.Case presentationWe describe 34-year-old female from north Indian state of Jammu and Kashmir who had presented with history of slowly increasing epigastric lump associated with abdominal discomfort of 4 months duration. She had no features of luminal obstruction. Her contrast enhanced computed tomography abdomen revealed a large extra-colonic mass in relation to transverse colon. The tumor was resected and histology was suggestive of gastrointestinal stromal tumor.ConclusionExtra luminal colonic gastrointestinal stromal tumors are very rare and can present as mass abdomen. Resection is the treatment of choice.

Highlights

Gastrointestinal stromal tumors are the commonest mesenchymal tumors of the gastrointestinal tract, the stomach and small intestine are the favored sites of occurrence
Case presentation: We describe 34-year-old female from north Indian state of Jammu and Kashmir who had presented with history of slowly increasing epigastric lump associated with abdominal discomfort of 4 months duration
gastrointestinal stromal tumors (GISTs) vary from spindle cell tumors to epithelioid and pleomorphic tumors

Summary

Introduction

Colonic gastrointestinal stromal tumors (GISTs) are very uncommon. Histologically GISTs vary from spindle cell tumors to epithelioid and pleomorphic tumors. The patient had maintained appetite and no weight loss She had no features of luminal obstruction. On examination, she was conscious, oriented with no pallor, lymphadenopathy edema or jaundice. The swelling was 7 × 6 cms in the epigastric region, globular with smooth margins It was firm in consistency and there was no splash or bruit on auscultation. Her evaluation revealed a Hb of 11.4 gm/dl (Normal 11-14 gm/dl) TLC 10,500 (Normal 400010000) Her kidney function tests, liver function tests were normal. The contrast enhanced computed tomography (CECT) abdomen revealed 8 × 7 cms mass lesion in relation to transverse colon (Figure 1) liver, spleen etc were normal. The overall features were suggestive of GIST (Figure 3)

Findings

Discussion

Conclusion