Abstract
We conducted an external quality assessment of Zika virus molecular diagnostic tests in Brazil using a new Zika virus standard. Of 15 laboratories, 73% showed limited sensitivity and specificity. Viral load estimates varied significantly. Continuous quality assurance is required for adequate estimates of Zika virus–associated disease and determination of patient care.
Highlights
Ana Maria Bispo de Filippis, Antonio Carlos Rosário Vallinoto, Bergmann Morais Ribeiro, Edison Luiz Durigon, Ernesto T.A
Zika virus molecular diagnostic testing is challenged by short-term viremia and low viral loads [3]
Laboratories in affluent countries conduct Zika virus diagnostic testing predominantly in travelers returning from tropical regions
Summary
Ana Maria Bispo de Filippis, Antonio Carlos Rosário Vallinoto, Bergmann Morais Ribeiro, Edison Luiz Durigon, Ernesto T.A. We conducted an external quality assessment of Zika virus molecular diagnostic tests in Brazil using a new Zika virus standard. Zika virus molecular diagnostic testing is challenged by short-term viremia and low viral loads [3]. Laboratories in affluent countries conduct Zika virus diagnostic testing predominantly in travelers returning from tropical regions.
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