Abstract
Certain bacteria cause excystment of Acanthamoeba from cyst to trophozoite form and are then ingested by migrating trophozoites. We studied the response of Acanthamoeba cysts to inoculation on agar seeded with three types of commensal eye bacteria and Escherichia coli. Amoebae excysted on all bacteria tested, and the migration rate of Acanthamoeba trophozoites on each was compared. Acanthamoeba migrated with equal speed on E. coli and Staphylococcus epidermidis. Migration was observed, but was more slow on Micrococcus and Corynebacterium. Commensal bacteria on the eyelids, conjunctiva and tear film may have a role in pathogenesis of Acanthamoeba keratitis.
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