Extensive subdural ossification with meningioma

Abstract

Abstract Rationale: Intracranial tumors can stimulate the occurrence of intracranial ossification, and previous studies have reported intracranial ossification with astrocytoma, glioblastoma multiforme and growth hormone adenoma. For meningiomas derived from arachnoid cells, the outcome of abnormal arachnoid cells is not only tumorigenesis, but also calcium deposition. To the best of our knowledge, meningioma with subdural ossification has not been reported. Patient concerns: A 60 year old woman was admitted to the hospital with a 1-year-old history of right blepharoptosis. Diagnoses: The preoperative examination of the patient was suggestive of meningioma on magnetic resonance imaging plain scan and enhancement. After the surgery, Endothelial cell type meningioma (WHO I grade) with intracranial ossification was diagnosed. Interventions: The patient underwent right extended pterional approach craniotomy and the neoplasm was gross totally resected. The patient was scheduled for follow-up and regular observation of the intracranial ossification. Outcomes: Intracranial computed tomography showed that extensive ossification still existed, but the symptoms of right blepharoptosis were significantly improved. Lessons: The authors report a rare case of meningioma complicated with extensive subdural ossification. Further studies are needed to confirm whether intracranial ossification in meningioma is related to arachnoid granulosa cells.