Extensive Squamous Papillomatosis of the Esophagus

Abstract

Although small solitary esophageal papillomas are uncommon findings that are occasionally identified on routine upper endoscopies, extensive papillomatosis is an extremely rare condition, with only 10 cases reported in the English literature. Although it is not known if solitary esophageal papillomas are premalignant lesions, papillomatosis carries a high risk of malignant transformation, and squamous cell carcinomas were identified in 6 out of 10 reported cases of extensive papillomatosis. We present the case of a 72-year-old woman with a newly diagnosed papillomatosis that affects the esophagus subtotally. The papillar alterations harbored a poorly defined early squamous cell carcinoma. This article is part of an expert video encyclopedia.