Abstract
Spindle cell carcinoma (SpCC) is considered a rare high malignant variant of squamous cell carcinoma (SCC) occurring predominantly in the upper aerodigestive tract. Lane tumor is a synonym for SpCC and is an uncommon poorly differentiated type of SCC comprising up to 3%. SpCC most commonly occurs in the sixth to seventh decades of life and usually affects men. A 66-year-old white patient was presenting an extensive ulcerated lesion affecting the lower lip with infiltrative fibroelastic consistency, local symptomatology, and 1 year of evolution. An incisional biopsy was performed, and the histopathologic findings were compatible with SpCC. Immunohistochemistry was also performed, which showed positivity for S-100. The association of clinical and histopathologic characteristics and the immunohistochemical analysis led to the diagnosis of SpCC. The patient was guided and referred to a head and neck surgeon for treatment.
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