Extensive Molluscum Contagiosum in X-Linked Agammaglobulinemia

Abstract

X-linked agammaglobulinemia (XLA) is among the most common inborn errors of immunity. The usual clinical phenotype is an increased susceptibility to bacterial and enteroviral infections; however, other viral infections, which result in chronic, severe, or recurrent infections, are being increasingly reported in XLA. These include respiratory viruses, herpesviruses, hepatotropic viruses, and more rarely members from astrovirus and orthobunyavirus families.1 Molluscum contagiosum, a poxvirus, has not been reported in patients with XLA.