Abstract
An unusual case of extensive pulmonary metastatic calcification occurring during the course of chronic pyelonephritis is described. The important features of this case are as follows: (1) Metastatic calcification appeared to develop in an early state of chronic renal failure when there was neither hypercalcemia, hyperphosphatemia, hyperparathyroidism nor evidence of bone disease. (2) The calcium and phosphate ion product was normal during the last 3 years when the pulmonary metastatic deposits persisted and progressed with the roentgenologic appearance of pulmonary edema. (3) There was calcium carbonate rather than the anticipated calcium phosphate in the deposited material. A review of the literature offers some theoretic explanation for the sites of calcification but no practical explanation for the presence of calcification.
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