Abstract
ST elevation myocardial infarction (STEMI) incidence rates has been decreased inversely to non-STEMI (121 to 77, 126 to 132 per 100.000 case respectively). Diabetes as a risk factors of STEMI is found in 20% patients. The increment of fibrinogen level in diabetic patient may induce compact clots resistance to fibrinolysis that lead to hypercoagulable state problem. Percutaneous coronary intervention (PCI), a non-surgical invasive procedure, can be done to relieve the obstruction. We reported two case reports, patients with anterior extensive STEMI who had underwent primary PCI. Both patients were found a total occlusion at proximal segment of LAD. First case was presented type 2 diabetes mellitus as comorbid while the second case was without diabetes. High burden thrombus was found on the diabetic patient which had poor prognosis, but on the non diabetic patient was found only less thrombus which was more stable condition. There is a strong correlation between type 2 diabetes mellitus and cardiovascular disease (CVD). Glucose control is important for prevention of CVD. Dietary changes that are characterized by increased use of natural sources diets such as whole grains, vegetables, and fruit-based foods and increased physical activity is remarkably strong factors for diabetes prevention.
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