Abstract
Problem: This study examines preoperative clinical characteristics that can be used to predict secure inferior margins of glottic squamous cell carcinoma (SCC) extending toward the cricoid cartilage, when performing organ preservation surgery of the larynx. Methods: Thirty-one serially sectioned whole-organ laryngectomies were histologically analyzed and true vocal cord (TVC) mobility, cricoarytenoid joint invasion, subglottic extension (SGE) of tumor, and prior radiation were examined as independent and multivariate correlates of cricoid invasion. Results: All tumors with SGE. Conclusion: Preoperative assessment of arytenoid mobility and extent of SGE are reliable predictors of cricoid invasion by glottic SCC. Significance: Organ preservation surgery is oncologically safe in the setting of glottic SCC with SGE. Support: None reported.
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