Abstract

Meeting abstracts Immune evasion by suppression of host immunity is one of the major mechanisms that tumors use to promote its own survival. We have reported an abundance of immunosuppressive monocytes (CD14+HLA-DRlow/neg) in lymphoma (LYM), multiple myeloma (MM), glioblastoma multiforme (GBM),

Highlights

  • Immune evasion by suppression of host immunity is one of the major mechanisms that tumors use to promote its own survival

  • We have reported an abundance of immunosuppressive monocytes (CD14+HLA-DRlow/neg) in lymphoma (LYM), multiple myeloma (MM), glioblastoma multiforme (GBM), prostate cancer and renal cell carcinoma (RCC)

  • We examine the RNA expression profile of monocytes from cancer patients compared to healthy donors (CNTRL) to identify differentially affected functional pathways

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Summary

Open Access

Expression profiling of suppressive monocytes (CD14+HLA-DRlow/neg) in cancer patients. Stefan F Cordes1*, Michael P Gustafson, Zhe Zhang, Peggy A Bulur, Dennis A Gastineau, Yi Lin, Allan B Dietz. From Society for Immunotherapy of Cancer 28th Annual Meeting National Harbor, MD, USA. From Society for Immunotherapy of Cancer 28th Annual Meeting National Harbor, MD, USA. 8-10 November 2013

Background
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