Abstract

Purpose/Objective: Until recently, radiation research has mainly focused on the tumor cell compartment. However, the genetically more stable microenvironment including the endothelial cell compartment has now been widely recognized to play a key role in radiation effects in vivo. One way to better understand radiation effects is the identification of genes regulated in response to radiation, which can affect the cell cycle, DNA repair, apoptosis, metastasis and angiogenesis. DNA microarray technology is now considered as an emerging technology to potentially explore cellular pathways. In order to better understand the effects of radiation on endothelial cells, we investigate here the gene expression profile of endothelial cells in response to ionizing radiation using a DNA chip.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.