Abstract

To assess expression patterns of MRPS18family genes in glioblastoma tissues and glioma cell lines. Expression of MRPS18family genes was analyzed by quantitative polymerase chain reaction in glioma cell lines and glioblastoma specimens. A bioinformatic analysis of the publicly available data on the expression of these genes was also provided. The genes of MRPS18family show different expression patterns in glioblastomas and glioma cell lines. The highest levels of expression were found for MRPS18-2at mRNA and protein levels in both glioblastomas and glioma cell lines; the lowest- for MRPS18-1at mRNA level. The elevated levels of relative expression of the MRPS18-2gene are characteristic for glioma tumor tissues and cell lines.

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