Abstract
OBJECTIVE: There are few predictors of the invasion and migration of the trophoblasts. More and more study indicated that Tspan5 proteins play an important role in migration of malignant tumor. The purpose of this study was to examine the expression of Tspan5 on the villus of early pregnancy, the hydatidiform mole, the invasive hydatidiform mole and the chorionic carcinoma tissue and determine its relationship to the invasion and migration of the trophoblasts.
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