Abstract

Objective: To analyze the expression and significance of TMEFF2 gene methylation in bladder cancer. Methods: The promoter region methylation level of the MEFF 2 gene was analyzed by applying the expression database and gene methylation.64 urine samples were detected by demethylated drug-nitrogen-2 deoxycytidine to observe the changes of cell invasion and apoptotic valence, and its application value in bladder cancer was analyzed by applying high expression of TMEFF2 gene. Results: Drug treatment of bladder cancer cells showed that the appreciation and migration of bladder cancer were inhibited, but the number of apoptosis increased. Conclusion: TMEFF2 gene promoter methylation is one of the markers of bladder cancer and plays an important role in the diagnosis of bladder cancer.

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